Glossary entry (derived from question below)
English term or phrase:
human CTLA4 KI, human CD3 EDG-replaced mice
Russian translation:
см.
Added to glossary by
Nitrogen
Jun 19, 2022 07:13
1 yr ago
7 viewers *
English term
human CTLA4 KI, human CD3 EDG-replaced mice
English to Russian
Science
Biology (-tech,-chem,micro-)
иммунология�
Efficacy of each of the anti-CTLA4 switch antibody and anti-CTLA4 non-switch antibody in a syngeneic tumor cell-transplanted model using human CTLA4 knock-in, human CD3 transgenic mouse, increase/decrease of Treg cells in tumor, and change in systemic response marker in the spleen
A ***human CTLA4 KI, human CD3 EDG-replaced mice*** (hCTLA4 KI hCD3 EDG-replaced mice), which is a hybrid of a human CTLA4 knock-in mouse and an in-house generated human CD3 EDG-replaced mouse was used.
A ***human CTLA4 KI, human CD3 EDG-replaced mice*** (hCTLA4 KI hCD3 EDG-replaced mice), which is a hybrid of a human CTLA4 knock-in mouse and an in-house generated human CD3 EDG-replaced mouse was used.
Proposed translations
(Russian)
| 3 | см. |
Igor Andreev
|
Proposed translations
1 hr
Igor Andreev
Native in Russian
Specializes in field
Native in: Russian 
Works in: English to Russian, Ukrainian to Russian, English to Ukrainian
Related KudoZ points
:
1427
Selected
см.
мыши/линия мышей с нокином человеческого гена CTLA4 KI и гуманизированным CD3 EDG
см.
https://www.proz.com/kudoz/english-to-russian/medical-genera...
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Note added at 1 day 4 hrs (2022-06-20 11:23:44 GMT) Post-grading
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простите, недосмотрел, когда копировал - лишнее KI:
мыши с нокином человеческого гена CTLA4 и гуманизированным CD3 EDG
см.
https://www.proz.com/kudoz/english-to-russian/medical-genera...
--------------------------------------------------
Note added at 1 day 4 hrs (2022-06-20 11:23:44 GMT) Post-grading
--------------------------------------------------
простите, недосмотрел, когда копировал - лишнее KI:
мыши с нокином человеческого гена CTLA4 и гуманизированным CD3 EDG
4 KudoZ points awarded for this answer.
Comment: "Thanks
"
Reference comments
36 mins
Reference:
I think you understand what replaced mice means. Anyway a remind:
In this study we have successfully established a novel mouse strain in which the entire CD3 components, i.e. CD3E, CD3D, and CD3G (referred to as CD3 EDG in this paper) were genetically humanized. - Entire CD3ε, δ, and γ humanized mouse to evaluate human CD3–mediated therapeutics - PMC (nih.gov)
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Note added at 42 minutos (2022-06-19 07:56:40 GMT)
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Humanized Mouse Models - https://www.creative-biolabs.com/drug-discovery/therapeutics...
In this study we have successfully established a novel mouse strain in which the entire CD3 components, i.e. CD3E, CD3D, and CD3G (referred to as CD3 EDG in this paper) were genetically humanized. - Entire CD3ε, δ, and γ humanized mouse to evaluate human CD3–mediated therapeutics - PMC (nih.gov)
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Note added at 42 minutos (2022-06-19 07:56:40 GMT)
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Humanized Mouse Models - https://www.creative-biolabs.com/drug-discovery/therapeutics...
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