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Translation - English Environmental calibration (V4.65.0.1) should be performed in Jaeger LabManager V4.65g before the Body Plethysmography Program (V4.66.7.0) is running.
Unit variation should not be greater than 1 °C, 10hPa and 10%rel.Hum, otherwise please refer to "calibration" MRI nzsop – Bowen.
Load correct settings immediately after Body Plethysmography Program (V4.66.7.0) is running.
Unless otherwise specified by the sponsor, the setting should be set to MRINZsop (these settings will then be named after the research identification code – e.g. ABC104960).
For the definition of these settings, see Appendix A – MRINZSOP Whole Body Plethysmography Settings.
Start the Body Plethysmography test immediately when the exhaled gas and body temperature of the subject causes an increase in the temperature of the inner box and the temperature of the body plethysmography box reaches a stable state.
The stability of the body plethysmography box mainly depends on the temperature variation caused by body heat, which can affect humidity and pressure.
4.1.
If the subject feels uncomfortable and asks to open the body plethysmography box before the reproduction standard is reached, the temperature of the inner box must be re-stabilized before the next test.
Resistance and conductivity should be measured before the measurement of lung volume and respiratory volume.
5.1.
After the Cheyne-Stokes breathing is established, the subject should be encouraged to increase the respiratory rate to 1.5 times/second and reduce the respiratory capacity accordingly. After 10 times of smooth breathing at this rate, the shutter will close and the subject will continue breathing.
Respiratory resistance should be measured at a respiratory rate of 1.5-2.5 times/second (AARC Guide:
body plethysmography), while ITGV should be measured at a respiratory rate of 1 time/second (AARC Guide:
Static Lung Volume), so we should take the lower respiratory rate as the indicator.
If the required rate is not reached within 15 seconds of starting Cheyne-Stokes breathing, the subject should take a short rest and then return to the next round of Cheyne-Stokes breathing to try again before the next measurement.
5.2.
The resistance and conductivity calculated by Body Plethysmography V4.66.7.0 (in LabManager V4.65g) are recorded immediately before the shutter closes.
The program cannot report arithmetic mean values (arithmetic mean values need to be calculated using copied values, which increases the probability of errors).
5.3.
The measurement should be made between 3 and 8 and will stop immediately after the reproduction standard is reached.
Each measurement value shall be kept in a separate file.
At the interval of each measurement, the subject should take a short rest and leave the mouthpiece.
Body Plethysmography V4.66.7.0 overwrites previously measured resistance values in the same file with the resistance values of subsequent measurements.
(Press F7 and then F9 to save existing files without exiting the program;
Press F1 to start a series of new values).
Lung volume test should be performed after the measurement of resistance and conductivity but before the measurement of respiratory volume.
Respiratory volume measurement should be performed after the measurement of resistance and conductivity.
These measurements shall be performed when the body Plethysmography box is open.
Subjects should not use any long-acting beta receptor agonist for at least 12 hours, or caffeine and short-acting beta receptor agonist for at least 6 hours, before performing the pre-bronchiectasis test.
The bronchodilator used in visit 1a was 4x mcg ipratropium bromide, which was administered through an nebuliser.
The bronchodilator used in visit 1b was 4x100mcg salbutamol, which was administered through an nebuliser.
Post-bronchiectasis testing should begin 30 minutes after administration.
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